A new trading day began on Monday, with Spyre Therapeutics Inc (NASDAQ: SYRE) stock price up 11.17% from the previous day of trading, before settling in for the closing price of $24.26. SYRE’s price has ranged from $10.91 to $29.06 over the past 52 weeks.
A company in the Healthcare sector has jumped its sales by 44.65% annually for the last half of the decade. Meanwhile, its annual earnings per share averaged 31.44%. With a float of $67.49 million, this company’s outstanding shares have now reached $77.59 million.
Spyre Therapeutics Inc (SYRE) Insider Updates
As we move forward, let’s examine how large-scale investors are investing in this stock of the Biotechnology Industry. The insider ownership of Spyre Therapeutics Inc is 13.02%, while institutional ownership is 77.01%. The most recent insider transaction that took place on Nov 03 ’25, was worth 1,049,778. In this transaction Chief Executive Officer of this company sold 45,000 shares at a rate of $23.33, taking the stock ownership to the 701,907 shares. Before that another transaction happened on Nov 03 ’25, when Company’s Director proposed sale 90,000 for $24.46, making the entire transaction worth $2,201,400.
Spyre Therapeutics Inc (SYRE) Performance Highlights and Predictions
In its latest quarterly report, released on 12/31/2024, the company reported earnings of -0.81 per share, which was $0.1 higher than the consensus estimate of $0.26. In terms of return on equity, this company recorded -19.55% in contrast with 50.0% return on Investment (trailing twelve months). Wall Street market experts anticipate that the next fiscal year will bring earnings of -0.66 per share during the current fiscal year.
According to the Wall Street analysts, stocks earnings will be around 31.44% per share during the next fiscal year. For the long-term projections, market analysts anticipate that the company’s EPS will surge by 1.23% during the next five years compared to 44.65% growth over the previous five years of trading.
Spyre Therapeutics Inc (NASDAQ: SYRE) Trading Performance Indicators
Here are Spyre Therapeutics Inc’s current performance indicators. According to the last quarter’s results, the stock had a quick ratio of 10.90.
For the trailing twelve months, Company’s Diluted EPS (Earnings per Share) is -2.18, a number that is poised to hit -0.72 in the next quarter and is forecasted to reach -2.79 in one year’s time.
Technical Analysis of Spyre Therapeutics Inc (SYRE)
Let’s dig in a bit further. During the last 5-days, its volume was 0.63 million. That was inferior than the volume of 0.68 million it reported in year-ago period. As of the previous 9 days, the stock’s Stochastic %D was 71.07%.
During the past 100 days, Spyre Therapeutics Inc’s (SYRE) raw stochastic average was set at 98.11%, which indicates a significant increase from 96.04% during the past two weeks. Based on volatility metrics of the stock, it showed a historical volatility of 1.64 in the past 14 days, which was higher than the 1.12 volatility it showed in the past 100 days.
At the time of writing, stock’s 50-day Moving Average is $20.65, while its 200-day Moving Average is $17.53. However, in the short run, Spyre Therapeutics Inc’s stock first resistance to watch stands at $27.93. Second resistance stands at $28.88. The third major resistance level sits at $30.56. If the price goes on to break the first support level at $25.30, it is likely to go to the next support level at $23.62. Assuming the price breaks the second support level, the third support level stands at $22.67.
Spyre Therapeutics Inc (NASDAQ: SYRE) Key Stats
With a market capitalization of 2.09 billion, the company has a total of 77,592K Shares Outstanding. Currently, annual sales are 0 K while annual income is -208,020 K. The company’s previous quarter sales were 0 K while its latest quarter income was -11,180 K.






